Chemical Biology

University of Queensland

Course Description

  • Course Name

    Chemical Biology

  • Host University

    University of Queensland

  • Location

    Brisbane, Australia

  • Area of Study

    Chemistry, Molecular Biology

  • Language Level

    Taught In English

  • Prerequisites

    CHEM1200, CHEM1010 or CHEM1030

  • Course Level Recommendations

    Upper

    ISA offers course level recommendations in an effort to facilitate the determination of course levels by credential evaluators.We advice each institution to have their own credentials evaluator make the final decision regrading course levels.

    Hours & Credits

  • Host University Units

    2
  • Recommended U.S. Semester Credits
    4
  • Recommended U.S. Quarter Units
    6
  • Overview

    Course Description
    This course focuses on the application of principles of inorganic & organic chemistry to the understanding of biological function at the molecular level. Topics covered will include functional group chemistry in a biological setting, mechanistic enzymology, chemistry of coenzymes & vitamins, chemistry of biosynthetic pathways, computational & spectroscopic methods in chemical biology, metal ion acquisition & speciation in biological systems, metallo-proteins, role of metal ions in disease states. This is a key course for those undertaking the Chemical Biology stream of the Chemical Sciences dual major & for students wishing to continue with Chemistry that is relevant to Biological & Biomedical Sciences.

    Course Introduction
    CHEM2052 has been created in response to the changing face of research and its increasing multidisciplinary nature. Biological research is becoming increasingly molecular and a working knowledge of the chemical processes and their mechanisms is essential in the interpretation of data generated by biological experiments. Likewise, chemical research is rarely done in isolation from other fields and chemists are often required to use their chemical skills to investigate, manipulate and affect biological systems; especially in growth research areas such as pharmaceutical science and molecular engineering. Chemical Biology provides a knowledge and skill set to students who will work at the interface between chemistry and biology. An understanding of the reactions and mechanisms involved in the major biological pathways and processes and the chemical characteristics of the important biological molecules as well as knowledge of techniques used to investigate biological molecules are essential tools in the repertoire of any scientific researcher in the 21st century.

    Learning Objectives
    After successfully completing this course you should be able to:

    1. Use knowledge of fundamental chemistry to investigate and understand complex biological systems and processes;
    2. Evaluate and interpret information from various sources, distilling the essential and accurate facts and communicating these concisely and accurately to an audience.
    3. Investigate and evaluate the chemical processes which occur in biological systems using a molecular mechanistic strategy and thus recognise the interconnectedness of these processes.
    4. Understand the structure and electronic configuration of the major functional groups present in biological molecules and how these characteristics dictate their reactivity.
    5. Understand the chemical processes occurring in the major metabolic and catabolic pathways and the role of chemical species such as cofactors and vitamins.
    6. Understand the essential role metals play in catalysis and transport in biological systems.
    7. Recognise and predict mechanisms by which enzymes catalyse chemical reactions including the path of electron flow in the reactions and recognize the multi-step processes that occur in an active site to achieve an overall transformation.
    8. Understand the various spectroscopic techniques used to investigate biological molecules and reactions. Appreciate where and how the different techniques might be used.

    Course Contact
    3 Lecture hours, 3 Contact hours

Course Disclaimer

Courses and course hours of instruction are subject to change.

Eligibility for courses may be subject to a placement exam and/or pre-requisites.

Some courses may require additional fees.

Credits earned vary according to the policies of the students' home institutions. According to ISA policy and possible visa requirements, students must maintain full-time enrollment status, as determined by their home institutions, for the duration of the program.