Molecular and Microbial Genetics
University of Otago
Dunedin, New Zealand
Area of Study
Genetics, Microbiology, Molecular Biology
Taught In English
CELS 191 and CHEM 191 and 36 further points
Course Level Recommendations
ISA offers course level recommendations in an effort to facilitate the determination of course levels by credential evaluators.We advice each institution to have their own credentials evaluator make the final decision regrading course levels.
Recommended U.S. Semester Credits3 - 4
Recommended U.S. Quarter Units4 - 6
Hours & Credits
OverviewMutations; genetic analysis in bacteria; mobile genetic elements; genetic analysis of regulatory circuits; DNA cloning and sequencing in genetic analysis; comparative microbial genomics; genetics and evolution of viruses of eukaryotes.GENE 221 provides foundation material on molecular and microbial genetics. Topics include mutation, gene transfer and genetic analysis in bacteria, DNA cloning, and comparative genomics of bacteria, fungi and the HIV retrovirus. Discoveries and methodologies in microbial genetics underlie all aspects of modern biology and therefore this paper is directly relevant for students with an interest in any of the biological sciences. The lecture course is complemented by a laboratory course that includes four experiments that together give hands-on experience of many of the genetic principles that are discussed in the lectures.
The lecture course is divided into 6 modules:
-Mutations - the basis of geneticsGene transfer and genetic analysis in bacteria
-Genetic analysis of regulatory circuits
-Comparative microbial genomics and evolution
-Comparative fungal genomics
-Genetics of HIV
The lecture course is complemented by a laboratory course, which provides training in relevant genetic methods and data analysis, including mutagen detection using the Ames test, gene mapping by conjugation, transposon mutagenesis and DNA cloning using a plasmid vector.
The broad objectives of GENE 221 are to understand:
-The molecular basis and significance of mutation
-Classical genetics of bacteria
-The genetic approaches used in analysing gene regulation in bacteria
-DNA cloning as a tool for genetic analysis
-The use of comparative genomics in understanding the evolution of bacteria, yeast, other fungi and the HIV retrovirus
The recommended text book for GENE 221 is:
Introduction to Genetic Analysis (Griffiths, Wessler, Lewontin, Gelbart, Suzuki and Miller), 10th Edition. The 9th Edition of this book is also satisfactory if you have access to a copy.
Courses and course hours of instruction are subject to change.
Eligibility for courses may be subject to a placement exam and/or pre-requisites.
Some courses may require additional fees.
Credits earned vary according to the policies of the students' home institutions. According to ISA policy and possible visa requirements, students must maintain full-time enrollment status, as determined by their home institutions, for the duration of the program.
Please reference fall and spring course lists as not all courses are taught during both semesters.
Availability of courses is based on enrollment numbers. All students should seek pre-approval for alternate courses in the event of last minute class cancellations
Please note that some courses with locals have recommended prerequisite courses. It is the student's responsibility to consult any recommended prerequisites prior to enrolling in their course.