Sign In With Google
Course Description
-
Course Name
From molecules to cells: a translational path towards novel therapeutics
-
Host University
Università Cattolica del Sacro Cuore, Rome Campus
-
Location
Rome, Italy
-
Area of Study
Global Health, Health Science
-
Language Level
Taught In English
-
Prerequisites
Basic knowledge in chemistry and biochemistry
General biology
Ground knowledge in human genetics
-
ECTS Credits
6 -
Recommended U.S. Semester Credits3
-
Recommended U.S. Quarter Units4
Hours & Credits
-
Overview
COURSE OVERVIEW
This course will delve into innovative strategies for drug design, smart delivery, and biological testing exploited in modern medicine for the treatment of different conditions. Rooting on cellular and molecular mechanisms implicated in human diseases, a detailed emphasis will be devoted to explaining state-of-the-art biotechnologies, including, AI-based computational tools, biochemical assembly of nanocarriers, stem cells and advanced cellular models.
LEARNING OUTCOMES
- General disease mechanisms affecting cellular organelles and compartments
- Molecular cascades and signal transduction pathways enabling the identification of key molecular players
- Workflow for in silico protein modeling and drug design
- Drug delivery systems
- Stem cells and cell-based disease modeling
- Main functional assays exploited for in vitro drug testing.
Students will have the opportunity to delve into practical activities during simulated laboratory sessions, on paradigm disease models, aimed at acquiring technical competences for conducting an experimental path.
TEACHING METHODS
- Problem-based learning, self-learning, case studies and experiemental activities both in stimulated laboratory environments using online platforms for virtual laboraotry scenarios
EVALUATION
- Class participation (25%)
- Home and class assignments (25%)
- Final written exam (50%)