Experimental Cell Biology I

COURSE OBJECTIVE
The student has insight in biological processes fundamental in living cells. The student has an overview of techniques used in Cell Biology. The student can work with scientific literature.

COURSE CONTENT
We start with a brief repetition of basic Cell Biology and then go ahead with in-depth discussion of modern Cell Biology, with a particular focus on current and emerging experimental techniques. In Research Lectures, current topcis in Cell Biology will be discussed.

Topics:

• General cell organization and function, protein, DNA and RNA function, cell cycle and (programmed) cell death
• Transcription factors, gene expression, and epigenetics
• Protein modification, sorting, and membrane transport
• Receptors and signal transduction
• Basic techniques in Cell Biology (PCR, Electrophoresis, ELISA,
• Current models organisms in Cell Biology (e.g. E. coli, yeast, C. elegans, drosophila, zebra fish, mammalian models)
• Visualization techniques in Cell Biology Each student will also work on a literature assignment.

FORM OF TUITION
Lectures, work discussions related to the literature assignment, self-study in groups to repeat lecture material and for literature assignment

TYPE OF ASSESSMENT
Written exam (2/3), literature assignment (1/3)

RECOMMENDED BACKGROUND KNOWLEDGE
Basic (first and second year level) courses in Cell Biology

REMARKS
Compulsory portal course Minor Biomolecular Sciences and Neurosciences. This minor course requires a minimum of 25 participants to take place. This course is offered in week 1-4 of period 1 and is to be taken together with the accompanying course Experimental Cell Biology II. This course is based on first and second year level courses in Cell Biology.